Medical Use of Kanna
What is it?
By isolating this and other bio-chemically active compounds,
researchers are now confirming what many people have known for many
hundreds of years: that Sceletium has a remarkable ability to
effectively treat symptoms of anxiety.
Mesembrine is an alkaloid which is derived from the Sceletium
Tortuosum plant and is now being acknowledged as a key active
component in the ability of the plant to produce beneficial effects
(closely related to it are the alkaloids mesembrenone, mesembrenol
and tortuosamine, which are also present and produce very similar
effects to mesembrine).
It is a confirmed serotonin (re)-uptake inhibitor - as understood by
the US Patent office - which means that it regulates the effects of
one of the brain's most important neurotransmitters.
What are its benefits?
Individuals suffering from depression and anxiety can benefit
greatly from this substance.
Mesembrine works in the following manner: the brain is made up of
countless neurons, which transmit signals to each other only by
jumping the "gap" (synapse) to neighboring neurons. However, the
signal cannot jump the synapse without assistance.
The message can only travel when the neuron releases a
neurotransmitter to fill this gap and allow the signal to transient
The receiving neuron has many points on its surface that which act
as potential locks, each of which is known as a receptor and is
effected by a particular type of neurotransmitter. When sufficient
amounts of the neurotransmitter are received by the relevant
receptor, a nerve impulse is started and the message continues to
its ultimate destination. To permit recovery of the neuron to
receive new messages, the brain takes away the neurotransmitter from
the neuron receptors and permitting it to be sent back to the
originating nerves, a process known as re-uptake.
In individuals suffering from depression, the neurotransmitter
serotonin (also known as 5-hydroxytryptamine) is lacking. Mesembrine
slows down the re-uptake process, making it more probable there will
be more serotonin in the relevant receptors, greatly increasing the
possibility that there will be sufficient levels to set up the
signal transfer in all neighboring neurons.
Mesembrine allows the brain to function with reduced levels of
serotonin, allowing time for natural levels to build up, whereupon
the mesembrine dosage can be reduced or eliminated.
Are there any side effects?
Mesembrine will not produce any major side effects, but some
individuals will experience drowsiness, thus it must not be taken
before operating any type of machinery or. Also, it should not be
taken in conjunction with any other psychoactive substance or by
pregnant or nursing women, except under the supervision of your